RELN, reelin, 5649

N. diseases: 178; N. variants: 52
Disease: Otosclerosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0029899
Disease: Otosclerosis
Otosclerosis 		0.180 GeneticVariation disease BEFREE No association between variation in RELN and otosclerosis was observed in the whole cohort. 29728750 2018
CUI: C0029899
Disease: Otosclerosis
Otosclerosis 		0.180 Biomarker disease BEFREE It is surprising that no association was found between RELN and otosclerosis because the current analysis had very reasonable power and the RELN association has been published before in different articles using several independent populations. 24643032 2014
CUI: C0029899
Disease: Otosclerosis
Otosclerosis 		0.180 GeneticVariation disease BEFREE To analyze the role of reelin in otosclerosis, it has been studied in a case-control analysis for the polymorphism rs39335 in a southern Italy population. 24227897 2013
CUI: C0029899
Disease: Otosclerosis
Otosclerosis 		0.180 Biomarker disease BEFREE Between these conditions, the etiologic role of RELN is questionable in the pathogenesis of otosclerosis. 21630058 2012
CUI: C0029899
Disease: Otosclerosis
Otosclerosis 		0.180 GeneticVariation disease BEFREE Recently, a reelin gene, SNP rs3914132, located in intron 2, was shown to be associated with otosclerosis in a European population. 20882487 2010
CUI: C0029899
Disease: Otosclerosis
Otosclerosis 		0.180 Biomarker disease BEFREE These data further implicate RELN in the pathogenesis of otosclerosis. 19847460 2010
CUI: C0029899
Disease: Otosclerosis
Otosclerosis 		0.180 Biomarker disease BEFREE This suggests an influence of sex on the association of RELN with otosclerosis. 20642811 2010
CUI: C0029899
Disease: Otosclerosis
Otosclerosis 		0.180 GeneticVariation disease GWASDB A genome-wide analysis identifies genetic variants in the RELN gene associated with otosclerosis. 19230858 2009
CUI: C0029899
Disease: Otosclerosis
Otosclerosis 		0.180 GeneticVariation disease GWASCAT A genome-wide analysis identifies genetic variants in the RELN gene associated with otosclerosis. 19230858 2009
CUI: C0029899
Disease: Otosclerosis
Otosclerosis 		0.180 Biomarker disease BEFREE In conclusion, we provide evidence that implicates RELN in the pathogenesis of otosclerosis. 19230858 2009