HTRA1, HtrA serine peptidase 1, 5654

N. diseases: 164; N. variants: 45
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003864
Disease: Arthritis
Arthritis
0.020 AlteredExpression disease BEFREE LPS significantly increased HTRA-1 expression in the joint tissue as well as arthritis incidence and severity in mice with CIA. 23982886 2013
CUI: C0003864
Disease: Arthritis
Arthritis
0.020 AlteredExpression disease LHGDN Through identification of potential HtrA1 targets, studies presented herein propose that within the context of arthritis pathology HtrA1 contributes to cartilage degradation. 16377621 2006
CUI: C0003864
Disease: Arthritis
Arthritis
0.020 Biomarker disease BEFREE Through identification of potential HtrA1 targets, studies presented herein propose that within the context of arthritis pathology HtrA1 contributes to cartilage degradation. 16377621 2006