PSAP, prosaposin, 5660

N. diseases: 189; N. variants: 15
Disease: Prostatic Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.070 AlteredExpression group LHGDN Ectopic expression of neurotrophic peptide derived from saposin C increases proliferation and upregulates androgen receptor expression and transcriptional activity in human prostate cancer cells. 17712477 2007
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.070 AlteredExpression group LHGDN Prosaposin upregulates AR and PSA expression and activity in prostate cancer cells (LNCaP). 17044040 2007
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.070 AlteredExpression group LHGDN Prosaposin is a novel androgen-regulated gene in prostate cancer cell line LNCaP. 17171640 2007
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.070 AlteredExpression group LHGDN Saposin C stimulates growth and invasion, activates p42/44 and SAPK/JNK signaling pathways of MAPK and upregulates uPA/uPAR expression in prostate cancer and stromal cells. 15897971 2005
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.070 AlteredExpression group LHGDN Amplification and overexpression of prosaposin in prostate cancer. 16080200 2005
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.070 AlteredExpression group LHGDN Saposin C promotes survival and prevents apoptosis via PI3K/Akt-dependent pathway in prostate cancer cells. 15548330 2004
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.070 Biomarker group LHGDN Prosaptide TX14A stimulates growth, migration, and invasion and activates the Raf-MEK-ERK-RSK-Elk-1 signaling pathway in prostate cancer cells. 15305334 2004