PSAP, prosaposin, 5660

N. diseases: 189; N. variants: 15
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0243026
Disease: Sepsis
Sepsis
0.020 Biomarker disease BEFREE This may be correlated with renal injury in sepsis patients, since the kidney is thought to be a major secretor of prosaposin. 30279625 2018
CUI: C0243026
Disease: Sepsis
Sepsis
0.020 Biomarker disease BEFREE Isolates of Candida albicans from the oral cavities of subjects at different stages of human immunodeficiency virus (HIV) infection or uninfected controls were examined for (i) production of aspartic proteinase(s), a putative virulence-associated factor(s); (ii) the presence in the fungal genome of two major genes (SAP1 and SAP2) of the aspartic proteinase family; and (iii) experimental pathogenicity in a murine model of systemic infection. 8550193 1996