PSD, pleckstrin and Sec7 domain containing, 5662

N. diseases: 59; N. variants: 8
Disease: Mental disorders ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004936
Disease: Mental disorders
Mental disorders 		0.030 Biomarker group BEFREE Postsynaptic density (PSD) proteins have been implicated in the pathophysiology of neurodevelopmental and psychiatric disorders. 31616000 2019
CUI: C0004936
Disease: Mental disorders
Mental disorders 		0.030 Biomarker group BEFREE It is striking that 86% (6 of 7) of X-linked NRC/MASC genes and 49% (19 of 39) of X-chromosomal PSD genes are already known to be involved in human psychiatric disorders. 17236127 2007
CUI: C0004936
Disease: Mental disorders
Mental disorders 		0.030 Biomarker group BEFREE The characterization of synapse/PSD proteins is especially important in the light of recent data suggesting that several mental disorders have their molecular defect at the synapse/PSD level. 16865346 2006