TMPRSS4, transmembrane serine protease 4, 56649

N. diseases: 55; N. variants: 0
Disease: Primary malignant neoplasm of lung ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.070 Biomarker disease BEFREE Targeting of TMPRSS4 sensitizes lung cancer cells to chemotherapy by impairing the proliferation machinery. 30905815 2019
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.070 AlteredExpression disease BEFREE Future studies should determine the clinical value of assessing TMPRSS4 levels in different types of lung cancer. 27995596 2017
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.070 Biomarker disease BEFREE TMPRSS4 Expression as a Marker of Recurrence in Patients with Lung Cancer. 26722035 2016
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.070 PosttranslationalModification disease BEFREE Epigenetic alterations leading to TMPRSS4 promoter hypomethylation and protein overexpression predict poor prognosis in squamous lung cancer patients. 26989022 2016
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.070 Biomarker disease BEFREE Knockdown of TMPRSS4 reduced the proliferation rate in several lung cancer cell lines. 25414083 2015
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.070 AlteredExpression disease BEFREE However, molecular mechanisms leading to the protumorigenic regulation of TMPRSS4 in lung cancer are unknown. 24434435 2014
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.070 AlteredExpression disease BEFREE In all, 34 lung cancer cell lines were used to evaluate the TMPRSS4 expression. 22067904 2011