B2M, beta-2-microglobulin, 567

N. diseases: 352; N. variants: 6
Disease: Hemochromatosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018995
Disease: Hemochromatosis
Hemochromatosis 		0.220 Biomarker disease BEFREE Inhibition of β2-microglobulin/hemochromatosis enhances radiation sensitivity by induction of iron overload in prostate cancer cells. 23874600 2013
CUI: C0018995
Disease: Hemochromatosis
Hemochromatosis 		0.220 Biomarker disease MGD Mouse strains with point mutations in TAP1 and TAP2. 19721454 2010
CUI: C0018995
Disease: Hemochromatosis
Hemochromatosis 		0.220 GeneticVariation disease BEFREE The first important step toward establishing the role of HFE in the pathogenesis of HC came with the recent observation that the C282Y mutation disrupts the binding of beta 2-microglobulin to the HFE protein and as a result the mutant molecule is not expressed on the cell surface. 9723005 1998
CUI: C0018995
Disease: Hemochromatosis
Hemochromatosis 		0.220 Biomarker disease MGD Iron overload in beta 2-microglobulin-deficient mice. 8013958 1994