DPYSL5, dihydropyrimidinase like 5, 56896

N. diseases: 57; N. variants: 3
Disease: Neuropathy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0442874
Disease: Neuropathy
Neuropathy 		0.020 GeneticVariation group BEFREE Anticollapsin-responsive mediator protein 5 (CRMP-5) IgG is an antibody generally associated with small-cell lung cancer, which is known to cause paraneoplastic neurological syndromes, including encephalitis, myelitis and neuropathy. 31118171 2019
CUI: C0442874
Disease: Neuropathy
Neuropathy 		0.020 Biomarker group BEFREE Compared to ANNA1 alone, CRMP5 neuropathy has a higher prevalence of pain (79% vs 46%, <i>p</i> = 0.008), asymmetric polyradiculoneuropathy (54% vs 12%, <i>p</i> < 0.001), and inflammatory spinal fluids (elevated CSF protein or nucleated cell count 92% vs 60%, <i>p</i> = 0.022). 29222126 2018