|
Parkinson Disease
|
0.170 |
GeneticVariation
|
disease |
BEFREE |
Here, in order to discover potential AD-related loci, we investigated the association between late-onset AD (LOAD) susceptibility and nine single-nucleotide polymorphisms (SNPs) (rs11724635 of BST1, rs12637471 of MCCC1, rs15553999 of TMEM229, rs17649553 of MAPT, rs34311866 of TMEM175-GAK-DGKQ, rs356182 of SNCA, rs6430538 of ACMSD-TMEM163, rs76904798 of LRRK2 and rs823118 of RAB7L1-NUCKS1) which were reported to have genome-wide significant associations with PD risk in a recent Genome Wide Association Study performed among white population.
|
26738859 |
2017 |
|
Parkinson Disease
|
0.170 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association study of Parkinson's disease in East Asians.
|
28011712 |
2017 |
|
Parkinson Disease
|
0.170 |
GeneticVariation
|
disease |
GWASCAT |
A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci.
|
28892059 |
2017 |
|
Parkinson Disease
|
0.170 |
GeneticVariation
|
disease |
BEFREE |
Overall, we replicate associations at SNCA, LRRK2, MCCC1 and 14 other European PD loci but did not identify Asian-specific loci with large effects (OR > 1.45) on PD risk.
|
28011712 |
2017 |
|
Parkinson Disease
|
0.170 |
GeneticVariation
|
disease |
BEFREE |
We used 2 PD case-control data sets (Washington University and the Parkinson's Progression Markers Initiative) to determine whether polymorphisms located at the GWAS top hits (GBA, ACMSD/TMEM163, STK39, MCCC1/LAMP3, GAK/TMEM175, SNCA, and MAPT) show association with AAO or motor progression.
|
26601739 |
2016 |
|
Parkinson Disease
|
0.170 |
GeneticVariation
|
disease |
BEFREE |
Previous studies identified that polymorphisms RAB7L1/NUCKS1 rs823118, MCCC1 rs12637471 and STK39 rs1955337 to be the risk loci for Parkinson's disease (PD) in a Caucasian population.
|
26914237 |
2016 |
|
Parkinson Disease
|
0.170 |
GeneticVariation
|
disease |
BEFREE |
A meta-analysis of datasets from five Parkinson's disease GWAS from the USA and Europe found 11 loci that surpassed the threshold for genome-wide significance (p<5×10(-8)), and five were newly identified loci (ACMSD, STK39, MCCC1/LAMP3, SYT11 and CCDC62/HIP1R).
|
24631562 |
2014 |
|
Parkinson Disease
|
0.170 |
GeneticVariation
|
disease |
GWASCAT |
Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease.
|
25064009 |
2014 |
|
Parkinson Disease
|
0.170 |
GeneticVariation
|
disease |
BEFREE |
The first large-scale meta-analysis of published genome-wide association studies (GWAS) in Parkinson's disease (PD) identified 5 new genetic loci (ACMSD, STK39, MCCC1/LAMP3, SYT11, and CCDC62/HIP1R).
|
24312176 |
2013 |
|
Parkinson Disease
|
0.170 |
GeneticVariation
|
disease |
BEFREE |
In this study, we confirmed that the A allele of MCCC1/LAMP3 (rs11711441) polymorphism reduces the risk to develop sporadic PD (P = 0.043).
|
23496138 |
2013 |
|
Parkinson Disease
|
0.170 |
GeneticVariation
|
disease |
GWASDB |
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.
|
22438815 |
2012 |
|
Parkinson Disease
|
0.170 |
GeneticVariation
|
disease |
GWASDB |
Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2.
|
22451204 |
2012 |
|
Parkinson Disease
|
0.170 |
GeneticVariation
|
disease |
GWASCAT |
Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.
|
21738487 |
2011 |
|
Parkinson Disease
|
0.170 |
GeneticVariation
|
disease |
GWASDB |
Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.
|
21738487 |
2011 |
|
Parkinson Disease
|
0.170 |
GeneticVariation
|
disease |
GWASCAT |
Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies.
|
21292315 |
2011 |
|
Parkinson Disease
|
0.170 |
GeneticVariation
|
disease |
GWASDB |
Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies.
|
21292315 |
2011 |