Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0010823
Disease: Cytomegalovirus Infections
Cytomegalovirus Infections
0.010 AlteredExpression group BEFREE Interestingly, EBV and CMV infections modulate CTNNBIP1 expression. 30076728 2019
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.010 AlteredExpression group BEFREE Our data revealed a significant downregulation of CTNNBIP1 in gastric tumors. 30076728 2019
CUI: C0042769
Disease: Virus Diseases
Virus Diseases
0.010 AlteredExpression group BEFREE CTNNBIP1 downregulation is associated with tumor grade and viral infections in gastric adenocarcinoma. 30076728 2019
CUI: C0149678
Disease: Epstein-Barr Virus Infections
Epstein-Barr Virus Infections
0.010 AlteredExpression group BEFREE In the absence of EBV infection, lower expression of CTNNBIP1 was observed. 30076728 2019
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.010 AlteredExpression disease BEFREE In agreement with these findings, a low level of CTNNBIP1 was found to be correlated with a high level of MMP7 when a publicly available microarray dataset for lung cancer was analyzed. 31766223 2019
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
0.010 Biomarker disease BEFREE Our findings revealed the tumor suppressor role for CTNNBIP1 in gastric adenocarcinoma. 30076728 2019
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.010 AlteredExpression disease BEFREE In agreement with these findings, a low level of CTNNBIP1 was found to be correlated with a high level of MMP7 when a publicly available microarray dataset for lung cancer was analyzed. 31766223 2019
Infection caused by Helicobacter pylori
0.010 AlteredExpression disease BEFREE In the present study, we examined CTNNBIP1 gene expression, the methylation status of the regulatory region of the gene, and their association with Epstein-Barr virus (EBV), and cytomegalovirus (CMV) and Helicobacter pylori infections in human gastric adenocarcinoma tissues in comparison with their adjacent nontumoral tissues. 30076728 2019
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung
0.010 AlteredExpression disease BEFREE In agreement with these findings, a low level of CTNNBIP1 was found to be correlated with a high level of MMP7 when a publicly available microarray dataset for lung cancer was analyzed. 31766223 2019
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.010 Biomarker group BEFREE Linc00210 drives Wnt/β-catenin signaling activation and liver tumor progression through CTNNBIP1-dependent manner. 29540185 2018
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.010 AlteredExpression disease BEFREE CircRNA circRNA_102171 promotes papillary thyroid cancer progression through modulating CTNNBIP1-dependent activation of β-catenin pathway. 30424816 2018
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.010 Biomarker disease BEFREE The present study demonstrates a role for ICAT in MIS/AMH mediated inhibition of the Wnt signaling pathway in ovarian cancer. 28197641 2017
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary
0.010 Biomarker disease BEFREE The present study demonstrates a role for ICAT in MIS/AMH mediated inhibition of the Wnt signaling pathway in ovarian cancer. 28197641 2017
CUI: C2267227
Disease: Bulimia Nervosa
Bulimia Nervosa
0.010 Biomarker disease BEFREE These findings suggest that emotion regulation and self-directed behavior are important treatment targets and that ICAT-BN and CBT-E are comparable in modifying these psychological processes among individuals with BN. 28117906 2017
CUI: C4721610
Disease: Carcinoma, Ovarian Epithelial
Carcinoma, Ovarian Epithelial
0.010 Biomarker disease BEFREE The present study demonstrates a role for ICAT in MIS/AMH mediated inhibition of the Wnt signaling pathway in ovarian cancer. 28197641 2017
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.010 Biomarker disease BEFREE Frequent methylation (44-45%) than deletion (20-32%) with overall alterations of 52-55% was observed in MCC/CTNNBIP1 in the BC samples. 27208794 2016
CUI: C0152013
Disease: Adenocarcinoma of lung (disorder)
Adenocarcinoma of lung (disorder)
0.010 Biomarker disease BEFREE The identification of this functional miR-214-CTNNBIP1 interaction that regulates self-renewal in CSLCs has the potential to direct the development of novel therapeutic strategies for LAC. 26299367 2015
CUI: C0007103
Disease: Malignant neoplasm of endometrium
Malignant neoplasm of endometrium
0.010 Biomarker disease BEFREE ICAT-labeled normal and endometrial cancer (EC) tissues were analyzed with multidimensional liquid chromatography followed by tandem mass spectrometry. 24252907 2013
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma
0.010 Biomarker disease BEFREE ICAT-labeled normal and endometrial cancer (EC) tissues were analyzed with multidimensional liquid chromatography followed by tandem mass spectrometry. 24252907 2013
CUI: C0079218
Disease: Fibromatosis, Aggressive
Fibromatosis, Aggressive
0.010 GeneticVariation disease LHGDN Correlation between beta-catenin widespread nuclear expression and matrix metalloproteinase-7 overexpression in sporadic desmoid tumors. 18715618 2008
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
0.010 GeneticVariation disease BEFREE We have screened seven genes known to reside in or very close to this overlap consensus region, UBE4B/UFD2, KIF1B, DFFA, PGD, CORT, PEX14, and ICAT, for coding mutations in NBL tumor DNA. 12700669 2003
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.010 GeneticVariation disease BEFREE We have screened seven genes known to reside in or very close to this overlap consensus region, UBE4B/UFD2, KIF1B, DFFA, PGD, CORT, PEX14, and ICAT, for coding mutations in NBL tumor DNA. 12700669 2003
CUI: C4086165
Disease: Childhood Neuroblastoma
Childhood Neuroblastoma
0.010 GeneticVariation disease BEFREE We have screened seven genes known to reside in or very close to this overlap consensus region, UBE4B/UFD2, KIF1B, DFFA, PGD, CORT, PEX14, and ICAT, for coding mutations in NBL tumor DNA. 12700669 2003
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.010 AlteredExpression disease BEFREE Our results suggest that ICAT is not the putative tumor suppressor on 1p36.1-p36.2, although aberrant overexpression of ICAT may play a role in the pathogenesis of colorectal carcinomas. 12417602 2002
CUI: C0014170
Disease: Endometrial Neoplasms
Endometrial Neoplasms
0.010 AlteredExpression group LHGDN Loss of gamma-Catenin expression in squamous differentiation in endometrial carcinomas. 12068170 2002