Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0233794
Disease: Memory impairment
Memory impairment
0.310 GeneticVariation phenotype BEFREE After the onset of memory deficits in 3xTg-AD mice, a three weeks treatment with the selective A<sub>2A</sub>R antagonist normalized the up-regulation of hippocampal A<sub>2A</sub>R and restored hippocampal-dependent reference memory, as well as the decrease of hippocampal synaptic plasticity (60.0 ± 3.7% decrease of long-term potentiation amplitude) and the decrease of global (syntaxin-I) and glutamatergic synaptic markers (vGluT1). 29859867 2018
CUI: C0233794
Disease: Memory impairment
Memory impairment
0.310 Biomarker phenotype CTD_human Expression of VGLUTs contributes to degeneration and acquisition of learning and memory. 21295146 2011