DAZ2, deleted in azoospermia 2, 57055

N. diseases: 3; N. variants: 0
Disease: Male infertility ×
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0021364
Disease: Male infertility
Male infertility 		0.140 GeneticVariation phenotype BEFREE gr/gr-DAZ2-DAZ4-CDY1b deletion is a high-risk factor for male infertility in Tunisian population. 27457284 2016
CUI: C0021364
Disease: Male infertility
Male infertility 		0.140 GeneticVariation phenotype BEFREE Analysis of DAZ gene copies in Tunisian population, suggested that the simultaneous deletion of DAZ2 and DAZ4 gene copies is associated with male infertility, and that oligospermia seems to be promoted by removing DAZ4 copy. 24878370 2014
CUI: C0021364
Disease: Male infertility
Male infertility 		0.140 GeneticVariation phenotype BEFREE Association of DAZ1/DAZ2 deletion with spermatogenic impairment and male infertility in the South Chinese population. 23512232 2013
CUI: C0021364
Disease: Male infertility
Male infertility 		0.140 GeneticVariation phenotype BEFREE Together with published data, our analysis of DAZ gene copy suggested that the contribution of the different deletions to male infertility varies: only partial AZFc deletions removing DAZ1/DAZ2 seem to be associated with spermatogenic impairment, whereas those removing DAZ3/DAZ4 may have no or little effect on fertility. 15744033 2005