Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.030 GeneticVariation disease BEFREE Of the six different splicing isoforms of PDSS2, the five variants other than full-length PDSS2 showed loss of function in HCC. 29967258 2018
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.030 AlteredExpression disease BEFREE Decreased PDSS2 expression is an unfavorable prognostic factor for HCC, and PDSS2 has potent anticancer activity in HCC tissues and HepG2 cells. 25780306 2015
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.030 AlteredExpression disease BEFREE Mean expression levels of PDSS2 mRNA relative to that of uninvolved liver diminished gradually in the order of chronic hepatitis to cirrhosis, and each was significantly higher than those of HCCs. 25189544 2014