RAB25, RAB25, member RAS oncogene family, 57111

N. diseases: 53; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.040 Biomarker disease BEFREE The present study demonstrated that Rab25 mediated the sensitivity of ovarian cancer to cisplatin, a first‑line chemotherapeutic agent for the treatment of ovarian cancer in the clinic. 25405658 2015
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.040 Biomarker disease BEFREE To evaluate the role of RAB25 in ovarian cancer, RAB25 was knocked down by siRNA in HEY and ES‑2 human ovarian cancer cells. 22940905 2012
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.040 AlteredExpression disease BEFREE The expression of Rab25 correlated positively with AR expression supporting its role as an androgen responsive gene in ovarian cancer. 19623182 2009
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.040 Biomarker disease BEFREE Our data suggest that the Rab25 signalling pathway plays a role in the regulation of cell proliferation and apoptosis in ovarian cancer cells, which indicates that the Rab25 gene plays a definite role in the development and aggressiveness of human ovarian cancer and should be further elucidated as a possible therapeutic target of ovarian cancer. 17393986 2006
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.040 Biomarker disease LHGDN Our data suggest that the Rab25 signalling pathway plays a role in the regulation of cell proliferation and apoptosis in ovarian cancer cells, which indicates that the Rab25 gene plays a definite role in the development and aggressiveness of human ovarian cancer and should be further elucidated as a possible therapeutic target of ovarian cancer. 17393986 2006