PTEN, phosphatase and tensin homolog, 5728

N. diseases: 1349; N. variants: 384
Disease: Secondary malignant neoplasm of prostate ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0347001
Disease: Secondary malignant neoplasm of prostate
Secondary malignant neoplasm of prostate 		0.020 GeneticVariation disease BEFREE Rapid in vivo validation of candidate drivers derived from the PTEN-mutant prostate metastasis genome. 25592467 2015
CUI: C0347001
Disease: Secondary malignant neoplasm of prostate
Secondary malignant neoplasm of prostate 		0.020 GeneticVariation disease BEFREE The high mutation rate in advanced brain tumors, recent functional studies, and the high frequency of mutations in prostate metastases all strongly suggest that PTEN/MMAC1 alterations are involved in the formation of metastases. 10499615 1999