PTEN, phosphatase and tensin homolog, 5728

N. diseases: 1349; N. variants: 384
Disease: Tumor Expansion ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1519678
Disease: Tumor Expansion
Tumor Expansion 		0.020 AlteredExpression phenotype BEFREE In addition, PTEN overexpression or AMD3100 substantially inhibits tumor expansion in the lung. 31571016 2020
CUI: C1519678
Disease: Tumor Expansion
Tumor Expansion 		0.020 Biomarker phenotype BEFREE We propose that loss of PTEN during malignant progression contributes to tumor expansion through the deregulation of Akt activity and HIF-1-regulated gene expression. 10691731 2000