PTGER2, prostaglandin E receptor 2, 5732

N. diseases: 79; N. variants: 4
Disease: Status Epilepticus ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0038220
Disease: Status Epilepticus
Status Epilepticus 		0.020 Biomarker disease BEFREE A rat model of organophosphate-induced status epilepticus and the beneficial effects of EP2 receptor inhibition. 30818067 2020
CUI: C0038220
Disease: Status Epilepticus
Status Epilepticus 		0.020 Biomarker disease BEFREE Utilizing a bioavailable and brain-permeant compound, TG6-10-1, we found that pharmacological inhibition of EP2 receptor after a one-hour episode of kainate-induced status epilepticus (SE) in mice reduced seizure-promoted functional deficits, cytokine induction, reactive gliosis, blood-brain barrier impairment, and hippocampal damage. 30763657 2019