AICDA, activation induced cytidine deaminase, 57379
N. diseases: 265; N. variants: 16
Source: ALL
| Disease | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year |
|---|---|---|---|---|---|---|---|
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0.050 | Biomarker | disease | BEFREE | AID activation is widely observed in gastrointestinal tissues with cancer-associated inflammation, such as chronic viral hepatitis, Helicobacter pylori-related gastritis, Barrett's esophagus and inflammatory bowel disease. | 22469133 | 2012 |
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0.050 | AlteredExpression | disease | BEFREE | The aberrant expression of activation-induced cytidine deaminase (AICDA) was reportedly induced in gastric epithelial cells infected with cytotoxin-associated gene A (cagA)-positive Helicobacter pylori, resulting in the accumulation of alterations in the TP53 tumor suppressor gene in gastric cells. | 20373075 | 2010 |
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0.050 | AlteredExpression | disease | BEFREE | Helicobacter pylori-induced activation-induced cytidine deaminase expression and carcinogenesis. | 20667704 | 2010 |
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0.050 | Biomarker | disease | BEFREE | Modulation of activation-induced cytidine deaminase by curcumin in Helicobacter pylori-infected gastric epithelial cells. | 19889077 | 2009 |
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0.050 | AlteredExpression | disease | BEFREE | Helicobacter pylori increases the risk of gastric cancer development and triggers aberrant expression of activation-induced cytidine deaminase (AID). | 18391550 | 2007 |