PTGS2, prostaglandin-endoperoxide synthase 2, 5743

N. diseases: 1234; N. variants: 27
Disease: Glioma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017638
Disease: Glioma
Glioma 		0.400 Biomarker disease LHGDN Furthermore, our data show that pharmacological concentrations of celecoxib may interfere with the proapoptotic action of R(+)-MA and anandamide, suggesting that cotreatment with COX-2 inhibitors could diminish glioma regression induced by these compounds. 15361550 2004
CUI: C0017638
Disease: Glioma
Glioma 		0.400 AlteredExpression disease LHGDN The U87MG glioma cell line is a good model for COX-2 induction in glioma cell lines. 19029777 2008
CUI: C0017638
Disease: Glioma
Glioma 		0.400 AlteredExpression disease LHGDN We found that EGF-mediated stimulation of EGFR tyrosine kinase in human glioma cell lines induces expression of both COX-2 mRNA and protein. 17616668 2007