PTGS2, prostaglandin-endoperoxide synthase 2, 5743

N. diseases: 1234; N. variants: 27
Disease: Arthralgia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003862
Disease: Arthralgia
Arthralgia 		0.020 AlteredExpression phenotype BEFREE Both drugs improved joint pain and function, inhibited SF PGE(2) concentration, and induced a decrease in synovial COX-2 expression and synthesis not related to the tissue inflammatory status. 16476713 2006
CUI: C0003862
Disease: Arthralgia
Arthralgia 		0.020 Biomarker phenotype BEFREE Therefore, COX-2 antagonists may be indicated in the treatment of TMJ arthralgia. 11078133 2000