PTGS2, prostaglandin-endoperoxide synthase 2, 5743

N. diseases: 1234; N. variants: 27
Disease: Acoustic Neuroma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027859
Disease: Acoustic Neuroma
Acoustic Neuroma 		0.020 Biomarker disease BEFREE Furthermore, there was no apparent relationship between aspirin dosage, non-aspirin NSAID use, and COX-2 selectivity with VS growth, presenting tumor diameter at presentation, or mean VS growth rate. 28692590 2017
CUI: C0027859
Disease: Acoustic Neuroma
Acoustic Neuroma 		0.020 Biomarker disease BEFREE Overall, this work suggests that COX-2 is a key modulator in VS cell proliferation and survival and highlights salicylates as promising pharmacotherapies against VS. 25616959 2015