PTGS2, prostaglandin-endoperoxide synthase 2, 5743

N. diseases: 1234; N. variants: 27
Disease: Multiple adenomatous polyps ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0334294
Disease: Multiple adenomatous polyps
Multiple adenomatous polyps 		0.020 AlteredExpression disease BEFREE Previous reports reveal that defects of the tumor suppressor adenomatosis polyposis coli (APC) contribute to COX-2 upregulation in colon tumor cells. 19035518 2009
CUI: C0334294
Disease: Multiple adenomatous polyps
Multiple adenomatous polyps 		0.020 GeneticVariation disease BEFREE The COX-2 genotypes showed no association with the severity of duodenal adenomatosis. 19544971 2009