SLC12A5, solute carrier family 12 member 5, 57468

N. diseases: 135; N. variants: 20
Disease: Decompression Sickness ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011119
Disease: Decompression Sickness
Decompression Sickness 		0.010 AlteredExpression disease BEFREE Our results indicate the importance of even diminished levels of KCC2 in maintaining inhibitory signaling within the RT nucleus and suggest how this important activity choke point may be easily overcome in disorders such as epilepsy.<b>SIGNIFICANCE STATEMENT</b> Precise regulation of intracellular Cl<sup>-</sup> levels ([Cl<sup>-</sup>]<sub>i</sub>) preserves appropriate, often inhibitory, GABAergic signaling within the brain. 29273603 2018