Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025149
Disease: Medulloblastoma
Medulloblastoma
0.020 AlteredExpression disease BEFREE Taken together, our results identify key molecular players that regulate ADGRB1 gene expression in MB, demonstrate that reactivation of BAI1 expression underlies EPZ-6438 antitumorigenic action, and provide preclinical proof-of-principle evidence for targeting EZH2 in patients with MB. 31582835 2020
CUI: C0025149
Disease: Medulloblastoma
Medulloblastoma
0.020 Biomarker disease BEFREE Knockout of Adgrb1 in mice augments proliferation of cerebellar granule neuron precursors, and leads to accelerated tumor growth in the Ptch1<sup>+/-</sup> transgenic MB mouse model. 29894688 2018