INTS2, integrator complex subunit 2, 57508

N. diseases: 85; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma
0.030 GeneticVariation disease BEFREE To evaluate the frequency of ERBB2, INT2 and CMYC oncogene amplifications and their coexistence with PTEN gene mutations in endometrial carcinomas. 14663583 2004
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma
0.030 GeneticVariation disease BEFREE To investigate the potential clinical relevance of the amplification of the oncogenes c-erbB2, c-myc, and int-2 and the mutation of K-ras in endometrial cancer, 112 tumors were examined using PCR-based fluorescent DNA technology. 9885379 1999
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma
0.030 Biomarker disease BEFREE c-erbB-2 and FGF-3/INT-2 were amplified in a first group of 7 (14%) and a further group of 7 (14%) patients, respectively, of a total of 50 in whom endometrial cancer had been studied. 7697605 1995