PTN, pleiotrophin, 5764

N. diseases: 164; N. variants: 4
Disease: Choriocarcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0008497
Disease: Choriocarcinoma
Choriocarcinoma 		0.020 AlteredExpression disease BEFREE Our result shows that a retroviral Sp1 binding site in the PTN promoter is important for the expression of growth factor pleiotrophin in human choriocarcinoma cells.Oncogene (2000) 19, 3988 - 3998. 10962555 2000
CUI: C0008497
Disease: Choriocarcinoma
Choriocarcinoma 		0.020 AlteredExpression disease BEFREE This suggests that the tissue-specific expression of PTN due to the HERV insertion in the human genome supports the highly aggressive growth of human choriocarcinoma and possibly of the human trophoblast. 8962128 1996