|
Malignant Neoplasms
|
0.040 |
AlteredExpression
|
group |
BEFREE |
<i>In silico</i> analyses of The Cancer Genome Atlas data sets revealed consistent correlations between the expression of the transcripts encoding LRIG1 and its interactors ZBTB16 and PTPRK and inverse correlations between the transcripts encoding LRIG1 and GLRX3.
|
29317492 |
2018 |
|
Primary malignant neoplasm
|
0.040 |
AlteredExpression
|
group |
BEFREE |
<i>In silico</i> analyses of The Cancer Genome Atlas data sets revealed consistent correlations between the expression of the transcripts encoding LRIG1 and its interactors ZBTB16 and PTPRK and inverse correlations between the transcripts encoding LRIG1 and GLRX3.
|
29317492 |
2018 |
|
Degenerative polyarthritis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
PTPRK expression was higher in FLS from patients with RA versus patients with osteoarthritis, resulting from increased TGFB1 expression in RA FLS.
|
25378349 |
2016 |
|
melanoma
|
0.300 |
Biomarker
|
disease |
CTD_human |
Aggressiveness of human melanoma xenograft models is promoted by aneuploidy-driven gene expression deregulation.
|
22535842 |
2012 |
|
Celiac Disease
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease.
|
22057235 |
2011 |
|
Celiac Disease
|
0.100 |
GeneticVariation
|
disease |
GWASDB |
Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease.
|
22057235 |
2011 |
|
melanoma
|
0.300 |
Biomarker
|
disease |
CTD_human |
Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.
|
22842228 |
2012 |
|
Malignant neoplasm of breast
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Expression of PTPRK protein and gene transcript was examined in a cohort of breast cancer patients.
|
23552869 |
2013 |
|
Breast Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Expression of PTPRK protein and gene transcript was examined in a cohort of breast cancer patients.
|
23552869 |
2013 |
|
Colorectal Traditional Serrated Adenoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
Frequent PTPRK-RSPO3 fusions and RNF43 mutations in colorectal traditional serrated adenoma.
|
26924569 |
2016 |
|
Non-Small Cell Lung Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Furthermore, PTPRK was identified as a direct target of miR-1260b, and PTPRK expression was inversely correlated with miR-1260b in NSCLC cell lines and clinical tissues.
|
29628123 |
2018 |
|
mathematical ability
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.
|
30038396 |
2018 |
|
Asthma
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.
|
30929738 |
2019 |
|
Childhood asthma
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.
|
30929738 |
2019 |
|
Brain Waves
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genome-wide association analysis links multiple psychiatric liability genes to oscillatory brain activity.
|
29947131 |
2018 |
|
Epilepsy, Generalized
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies.
|
30531953 |
2018 |
|
Malignant neoplasm of prostate
|
0.310 |
Biomarker
|
disease |
CTD_human |
Identification of genes potentially involved in the acquisition of androgen-independent and metastatic tumor growth in an autochthonous genetically engineered mouse prostate cancer model.
|
17013881 |
2007 |
|
Prostatic Neoplasms
|
0.300 |
Biomarker
|
group |
CTD_human |
Identification of genes potentially involved in the acquisition of androgen-independent and metastatic tumor growth in an autochthonous genetically engineered mouse prostate cancer model.
|
17013881 |
2007 |
|
Malignant neoplasm of lung
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
In this study, we examined 75 primary CRCs and 121 primary lung cancers in the Japanese population for EIF3E-RSPO2 and PTPRK-RSPO3 fusion transcripts using RT-PCR and subsequent sequencing analyses.
|
24847761 |
2014 |
|
Eczema
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
Age at menarche
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
Malignant Neoplasms
|
0.040 |
Biomarker
|
group |
BEFREE |
Methylation of the phosphatase promoters was reversible with decitabine and a histone deacetylase inhibitor, suggesting that PTPRK-mediated cell signalling pathways may be targeted with epigenetic therapies in lymphoid malignancy.
|
24045499 |
2014 |
|
Primary malignant neoplasm
|
0.040 |
Biomarker
|
group |
BEFREE |
Methylation of the phosphatase promoters was reversible with decitabine and a histone deacetylase inhibitor, suggesting that PTPRK-mediated cell signalling pathways may be targeted with epigenetic therapies in lymphoid malignancy.
|
24045499 |
2014 |
|
Tumor Cell Invasion
|
0.020 |
Biomarker
|
phenotype |
BEFREE |
MiR-1260b promotes the migration and invasion in non-small cell lung cancer via targeting PTPRK.
|
29628123 |
2018 |
|
T-Cell Lymphoma
|
0.010 |
PosttranslationalModification
|
disease |
BEFREE |
Monoallelic deletion and promoter hypermethylation caused underexpression of PTPRK messenger RNA in NKTCL, and methylation of the PTPRK promoter significantly correlated with inferior overall survival (P = .049) in NKTCL patients treated with the steroid-dexamethasone, methotrexate, ifosfamide, l-asparaginase, and etoposide regimen.
|
25612622 |
2015 |