BAX, BCL2 associated X, apoptosis regulator, 581

N. diseases: 420; N. variants: 9
Disease: Fetal Growth Retardation ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0015934
Disease: Fetal Growth Retardation
Fetal Growth Retardation 		0.220 AlteredExpression phenotype BEFREE Our study revealed that it is the reduced inhibitory activity of the Bcl-2 gene rather than an enhanced stimulatory activity of the Bax gene in the background of the increased apoptosis observed in IUGR. 23038985 2013
CUI: C0015934
Disease: Fetal Growth Retardation
Fetal Growth Retardation 		0.220 Therapeutic phenotype RGD Antenatal supplementation of taurine for protection of fetal rat brain with intrauterine growth restriction from injury by reducing neuronal apoptosis. 22932950 2012
CUI: C0015934
Disease: Fetal Growth Retardation
Fetal Growth Retardation 		0.220 AlteredExpression phenotype BEFREE TP53-downstream apoptosis-related genes, such as BCL6 and BAX, were found to be significantly more up-regulated in pre-eclampsia than in FGR, although the caspases are expressed at equivalent levels. 21810232 2011