BAX, BCL2 associated X, apoptosis regulator, 581

N. diseases: 420; N. variants: 9
Disease: Congestive heart failure ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.220 AlteredExpression disease BEFREE Expression levels of IL-1ß, IL-6, TNF-alpha, and BAX mRNA were significantly associated with the degree of CHF. 30968846 2019
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.220 Therapeutic disease RGD Shenfu Formula reduces cardiomyocyte apoptosis in heart failure rats by regulating microRNAs. 29746994 2018
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.220 AlteredExpression disease BEFREE This study provides morphological evidence of renal injury during heart failure which may be due to caspase-mediated apoptosis via overexpression of proapoptotic Bax protein, subsequent mitochondrial cytochrome C release, and final nuclear transfer of activated caspase 3, supporting the notion of a cardiorenal syndrome. 28831296 2017
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.220 Therapeutic disease RGD Ethanol extract from Epimedium brevicornum attenuates left ventricular dysfunction and cardiac remodeling through down-regulating matrix metalloproteinase-2 and -9 activity and myocardial apoptosis in rats with congestive heart failure. 18097624 2008