PVALB, parvalbumin, 5816

N. diseases: 148; N. variants: 0
Disease: Heart Failure, Diastolic ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1135196
Disease: Heart Failure, Diastolic
Heart Failure, Diastolic 		0.010 Biomarker disease BEFREE This brief review summarizes the rationale and development of Parv gene transfer approaches for DHF, and in particular, discusses the divergent effects of Parv isoforms on cardiac myocyte Ca2+ handling and contractile function with the long-range goal of alleviating diastolic dysfunction in DHF. 18458829 2008