PYCR1, pyrroline-5-carboxylate reductase 1, 5831

N. diseases: 126; N. variants: 12
Disease: Reactive systemic amyloidosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0221014
Disease: Reactive systemic amyloidosis
Reactive systemic amyloidosis 		0.010 Biomarker disease BEFREE Peptides with disrupted helical structure [p5<sub>(coil)</sub> and p5<sub>(Pro3)</sub>], with an extended sheet conformation [p5<sub>(sheet)</sub>] or an all-D enantiomer [p5<sub>(D)</sub>], were chemically synthesized, radioiodinated, and their biodistribution studied in WT mice as well as transgenic animals with severe systemic AA amyloidosis. 28229334 2017