RAC1, Rac family small GTPase 1, 5879

N. diseases: 415; N. variants: 20
Disease: Adult Medulloblastoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0278876
Disease: Adult Medulloblastoma
Adult Medulloblastoma 		0.020 Biomarker disease BEFREE These data indicated that the invasion and migration in Daoy cells were inhibited by deletion of Rac1, and suggest that targeting Rac1 by Rac1 shRNA may further be evaluated and used as a potential anticancer strategy to treat medulloblastoma. 21076938 2011
CUI: C0278876
Disease: Adult Medulloblastoma
Adult Medulloblastoma 		0.020 Biomarker disease BEFREE Additionally, pharmacological inhibition of CaMKK blocks both the estrogen induced Rac1 activation and medulloblastoma migration. 21107644 2011