RAC1, Rac family small GTPase 1, 5879

N. diseases: 415; N. variants: 20
Disease: Tumor Angiogenesis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1519670
Disease: Tumor Angiogenesis
Tumor Angiogenesis 		0.040 Biomarker phenotype BEFREE Given the crucial roles of Rac1 in tumor angiogenesis and metastasis, intracellular mature IL-37 might serve as a potential strategy for the control of Rac1 activity and tumor progression. 29106392 2018
CUI: C1519670
Disease: Tumor Angiogenesis
Tumor Angiogenesis 		0.040 Biomarker phenotype BEFREE This review will focus on one master regulator of cell motility, RAC1, and the existing data with regard to its role in cell motility, including particular roles for tumor angiogenesis and invasion/metastasis. 24072884 2013
CUI: C1519670
Disease: Tumor Angiogenesis
Tumor Angiogenesis 		0.040 Biomarker phenotype BEFREE Examining the role of Rac1 in tumor angiogenesis and growth: a clinically relevant RNAi-mediated approach. 21789714 2011
CUI: C1519670
Disease: Tumor Angiogenesis
Tumor Angiogenesis 		0.040 Biomarker phenotype BEFREE Small GTPase Rac1, an inflammatory signaling mediator triggering reactive oxygen species (ROS) production by NADPH-oxidases, is implicated in carcinogenesis and tumor angiogenesis. 19429708 2009