RAD51, RAD51 recombinase, 5888

N. diseases: 363; N. variants: 16
Disease: Fever ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0015967
Disease: Fever
Fever 		0.020 Biomarker phenotype BEFREE The cytochrome C assay and the RAD51 focus formation assay are both feasible on freshly obtained bladder tumors, and could serve to predict the efficacy of hyperthermia together with cytotoxic agents, such as MMC or cisplatin. 30550547 2018
CUI: C0015967
Disease: Fever
Fever 		0.020 AlteredExpression phenotype BEFREE Prompted by this molecular insight into how hyperthermia attenuates homologous recombination, we now quantitatively explore time and temperature dynamics of hyperthermia on BRCA2 levels and RAD51 focus formation in cell culture models, and link this to their clonogenic survival capacity after irradiation (0-6 Gy). 28574821 2017