RAD51, RAD51 recombinase, 5888

N. diseases: 363; N. variants: 16
Disease: Thyroid Neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.020 AlteredExpression disease BEFREE The present study concluded that upregulation of RAD51 and overexpression of Ki67 may be associated with the progression of thyroid cancer. 28502582 2017
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.020 GeneticVariation disease BEFREE Since XRCC3 is involved in the assembly and stabilization of RAD51 protein multimers at double-strand break sites, we cannot exclude that the interaction of both polymorphisms can lead to a decreased DNA repair capacity and consequently increased risk for thyroid cancer. 19772428 2009