RAD51C, RAD51 paralog C, 5889

N. diseases: 162; N. variants: 96
Disease: bilateral breast cancer ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0281267
Disease: bilateral breast cancer
bilateral breast cancer 		0.010 GeneticVariation disease BEFREE Overall, 206 high risk women, 79 (38.3 %) of Ashkenazi origin, were genotyped for RAD51C mutations: 190 (92.3 %) with uni- or bilateral breast cancer (mean age at diagnosis 51.3 ± 11.1 years), 14 with ovarian cancer (mean age at diagnosis 55.6 ± 8.7 years), and two with both breast and ovarian cancer. 23117857 2012