BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
|
0.700 |
CausalMutation
|
disease |
CLINVAR |
Almost 2% of Spanish breast cancer families are associated to germline pathogenic mutations in the ATM gene.
|
27913932 |
2017 |
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
|
0.700 |
CausalMutation
|
disease |
CLINVAR |
Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.
|
26681312 |
2016 |
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
|
0.700 |
GeneticVariation
|
disease |
CLINVAR |
Hereditary truncating mutations of DNA repair and other genes in BRCA1/BRCA2/PALB2-negatively tested breast cancer patients.
|
26822949 |
2016 |
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
|
0.700 |
CausalMutation
|
disease |
CLINVAR |
Inherited Mutations in Women With Ovarian Carcinoma.
|
26720728 |
2016 |
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
|
0.700 |
GeneticVariation
|
disease |
CLINVAR |
Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.
|
26681312 |
2016 |
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
|
0.700 |
CausalMutation
|
disease |
CLINVAR |
Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population.
|
26261251 |
2015 |
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
|
0.700 |
CausalMutation
|
disease |
CLINVAR |
Patterns and functional implications of rare germline variants across 12 cancer types.
|
26689913 |
2015 |
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
|
0.700 |
GeneticVariation
|
disease |
CLINVAR |
Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population.
|
26261251 |
2015 |
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
|
0.700 |
GeneticVariation
|
disease |
CLINVAR |
Mutation Analysis of the RAD51C and RAD51D Genes in High-Risk Ovarian Cancer Patients and Families from the Czech Republic.
|
26057125 |
2015 |
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
|
0.700 |
CausalMutation
|
disease |
CLINVAR |
RAD51C germline mutations found in Spanish site-specific breast cancer and breast-ovarian cancer families.
|
25086635 |
2014 |
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
|
0.700 |
GeneticVariation
|
disease |
UNIPROT |
Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair.
|
24141787 |
2014 |
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
|
0.700 |
GeneticVariation
|
disease |
CLINVAR |
Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair.
|
24141787 |
2014 |
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
|
0.700 |
CausalMutation
|
disease |
CLINVAR |
Germline mutation in the RAD51B gene confers predisposition to breast cancer.
|
24139550 |
2013 |
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
|
0.700 |
GeneticVariation
|
disease |
CLINVAR |
Germline mutation in the RAD51B gene confers predisposition to breast cancer.
|
24139550 |
2013 |
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
|
0.700 |
GeneticVariation
|
disease |
UNIPROT |
Analysis of RAD51C germline mutations in high-risk breast and ovarian cancer families and ovarian cancer patients.
|
21990120 |
2012 |
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
|
0.700 |
GeneticVariation
|
disease |
CLINVAR |
Predominance of pathogenic missense variants in the RAD51C gene occurring in breast and ovarian cancer families.
|
22451500 |
2012 |
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
|
0.700 |
GeneticVariation
|
disease |
CLINVAR |
Germline RAD51C mutations confer susceptibility to ovarian cancer.
|
22538716 |
2012 |
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
|
0.700 |
GeneticVariation
|
disease |
CLINVAR |
Distinct roles of FANCO/RAD51C protein in DNA damage signaling and repair: implications for Fanconi anemia and breast cancer susceptibility.
|
22167183 |
2012 |
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
|
0.700 |
CausalMutation
|
disease |
CLINVAR |
Analysis of RAD51C germline mutations in high-risk breast and ovarian cancer families and ovarian cancer patients.
|
21990120 |
2012 |
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
|
0.700 |
CausalMutation
|
disease |
CLINVAR |
Germline RAD51C mutations confer susceptibility to ovarian cancer.
|
22538716 |
2012 |
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
|
0.700 |
CausalMutation
|
disease |
CLINVAR |
Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing.
|
22006311 |
2011 |
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
|
0.700 |
CausalMutation
|
disease |
CLINVAR |
A HRM-based screening method detects RAD51C germ-line deleterious mutations in Spanish breast and ovarian cancer families.
|
21537932 |
2011 |
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
|
0.700 |
CausalMutation
|
disease |
CLINVAR |
RAD51C is a susceptibility gene for ovarian cancer.
|
21616938 |
2011 |
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
|
0.700 |
CausalMutation
|
disease |
CLINVAR |
Further evidence for the contribution of the RAD51C gene in hereditary breast and ovarian cancer susceptibility.
|
21750962 |
2011 |
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
|
0.700 |
GeneticVariation
|
disease |
UNIPROT |
Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene.
|
20400964 |
2010 |