|
Adenocarcinoma of large intestine
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
|
27197191 |
2016 |
|
Adenocarcinoma of lung (disorder)
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
|
27197191 |
2016 |
|
Adult Fibrosarcoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
In addition, an approximately 50% reduction in RAD51B mRNA levels by RNA interference also leads to centrosome fragmentation in the human fibrosarcoma cell line HT1080.
|
16778173 |
2006 |
|
Adult Glioblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Our analysis revealed nine SNPs annotating MSH2, RAD51L1 and RECQL4 that were significantly (p < 0.05) associated with glioblastoma survival.
|
22017238 |
2012 |
|
Adult Lymphoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Next-generation sequencing analysis of the tumorous and normal tissue detected a pathogenic germline mutation of the FAM175A gene and somatic mutations in BRCA2 and RAD51B (in both sarcoma and lymphoma specimens), and INPP4B and RICTOR (in lymphoma specimen only).
|
31361614 |
2020 |
|
Age related macular degeneration
|
0.130 |
Biomarker
|
disease |
BEFREE |
This analysis revealed that 8 genetic variants (<i>CFH, ARMS2, IL-8, TIMP3, SLC16A8, RAD51B, VEGFA</i> and <i>COL8A1</i>) were significantly associated with AMD susceptibility.
|
29487693 |
2018 |
|
Age related macular degeneration
|
0.130 |
GeneticVariation
|
disease |
GWASDB |
Seven new loci associated with age-related macular degeneration.
|
23455636 |
2013 |
|
Age related macular degeneration
|
0.130 |
GeneticVariation
|
disease |
BEFREE |
We concluded that the risk of developing AMD exhibits dose dependency as well as an epistatic combined effect in rs17105278 T>C and rs4902566 C>T carriers and that the elevated risk for rs17105278 T>C carriers may be due to decreased transcription of RAD51B.
|
24526414 |
2014 |
|
Age related macular degeneration
|
0.130 |
Biomarker
|
disease |
BEFREE |
Among genetic variables, SNPs of CFH, ARMS2, IL-8, TIMP3, SLC16A8, RAD51B, VEGFA and COL8A1 were significantly associated with the risk of AMD in the Italian cohort.
|
29197628 |
2018 |
|
Age related macular degeneration
|
0.130 |
GeneticVariation
|
disease |
GWASCAT |
Seven new loci associated with age-related macular degeneration.
|
23455636 |
2013 |
|
Age related macular degeneration
|
0.130 |
GeneticVariation
|
disease |
GWASCAT |
A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.
|
26691988 |
2016 |
|
Allergic Reaction
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.
|
29083406 |
2017 |
|
Allergic Reaction
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.
|
29785011 |
2018 |
|
Asthma
|
0.110 |
Biomarker
|
disease |
BEFREE |
By linking DEGs to the genome-wide association study (GWAS) catalog and the lung and blood eQTL annotation data from GTEx, we identified four male-specific genes (FBXL7, ITPR3 and RAD51B from epithelial tissue and ALOX15 from blood) and one female-specific gene (HLA-DQA1 from epithelial tissue) that are disregulated during asthma.
|
31095684 |
2019 |
|
Asthma
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.
|
30929738 |
2019 |
|
Asthma
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.
|
31619474 |
2019 |
|
Asthma
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.
|
29785011 |
2018 |
|
Asthma
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
Detection and interpretation of shared genetic influences on 42 human traits.
|
27182965 |
2016 |
|
Autoimmune Diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
Dysregulation of RAD51L1 and/or BMP2 may explain this familial occurrence of thymomas and autoimmune diseases.
|
15942943 |
2005 |
|
Benign Neoplasm
|
0.010 |
Biomarker
|
group |
BEFREE |
Among them, Rad51B is unique in that the gene maps to the human chromosome 14q23-24, the region frequently involved in balanced chromosome translocations in benign tumors particularly in uterine leiomyomas.
|
16778173 |
2006 |
|
Biliary cirrhosis
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.
|
21399635 |
2011 |
|
Blood basophil count (lab test)
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
|
Body Height
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
Body Height
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Characterizing rare and low-frequency height-associated variants in the Japanese population.
|
31562340 |
2019 |
|
Body Height
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
|
20881960 |
2010 |