Disease: Small cell carcinoma of lung ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0149925
Disease: Small cell carcinoma of lung
Small cell carcinoma of lung 		0.070 Biomarker disease BEFREE Raf-1 causes growth suppression and alteration of neuroendocrine markers in DMS53 human small-cell lung cancer cells. 10100985 1999
CUI: C0149925
Disease: Small cell carcinoma of lung
Small cell carcinoma of lung 		0.070 AlteredExpression disease BEFREE Effects of c-raf-1 and c-myc expression on radiation response in an in vitro model of human small-cell-lung carcinoma. 9826556 1998
CUI: C0149925
Disease: Small cell carcinoma of lung
Small cell carcinoma of lung 		0.070 GeneticVariation disease BEFREE The cytogenetic and RFLP data suggest that the RAF1 locus at 3p25 is involved in the chromosomal deletion of SCLC. 1683566 1991
CUI: C0149925
Disease: Small cell carcinoma of lung
Small cell carcinoma of lung 		0.070 Biomarker disease BEFREE The tumors induced by the c-raf-1 and c-myc protooncogenes resemble the multidifferentiated phenotype of small cell lung cancer frequently detected in vivo and present a defined model to study the relation between molecular markers, phenotypical appearance, and response to chemotherapeutic agents and radiation. 1712250 1991
CUI: C0149925
Disease: Small cell carcinoma of lung
Small cell carcinoma of lung 		0.070 Biomarker disease BEFREE The p74c-raf1 protein was found in all non-SCLC cell lines. 2536917 1989
CUI: C0149925
Disease: Small cell carcinoma of lung
Small cell carcinoma of lung 		0.070 Biomarker disease BEFREE This striking loss of heterozygosity at the c-raf-1 locus in SCLC indicates that one allele of c-raf-1 is deleted in SCLC. 2566144 1989
CUI: C0149925
Disease: Small cell carcinoma of lung
Small cell carcinoma of lung 		0.070 AlteredExpression disease BEFREE Overexpression of c-raf-1 and the myc family of protooncogenes is primarily associated with small cell carcinoma, which accounts for approximately 25% of human lung cancer. 2557616 1989