RARA, retinoic acid receptor alpha, 5914

N. diseases: 225; N. variants: 3
Disease: Multiple Sclerosis ×
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.020 AlteredExpression disease BEFREE These results show that vitamin A supplementation can significantly downregulate the expression of RAR-α gene in PBMCs of MS patients that suggest the presence of in vivo regulatory mechanisms for the action of vitamin A on the immune system. 23955709 2013
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.020 GeneticVariation disease BEFREE Another shared breakpoint was identified within the approximately 17-kb RARA intron 2 involving 2 t-APL cases arising after mitoxantrone treatment for MS and breast cancer, respectively. 18650449 2008