RB1, RB transcriptional corepressor 1, 5925

N. diseases: 339; N. variants: 239
Disease: Sarcoma of soft tissue ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4551687
Disease: Sarcoma of soft tissue
Sarcoma of soft tissue 		0.030 Biomarker group BEFREE Retinoblastoma (RB1) gene involves in retinoblastoma, osteosarcoma, bladder, prostate, lung, breast carcinomas, and soft tissue sarcomas. 11919466 2002
CUI: C4551687
Disease: Sarcoma of soft tissue
Sarcoma of soft tissue 		0.030 GeneticVariation group BEFREE Mutation of the p53 gene in human soft tissue sarcomas: association with abnormalities of the RB1 gene. 2216456 1990
CUI: C4551687
Disease: Sarcoma of soft tissue
Sarcoma of soft tissue 		0.030 GeneticVariation group BEFREE Using a probe that detects a polymorphic locus within the RB1 gene we found loss of only one allele (heterozygous deletion) in 33% of soft tissue sarcomas examined, including two leiomyosarcomas, a malignant peripheral nerve sheath tumour, a rhabdomyosarcoma and a chondrosarcoma. 2765366 1989