CCND1, cyclin D1, 595

N. diseases: 859; N. variants: 12
Disease: Intestinal Polyps ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0021846
Disease: Intestinal Polyps
Intestinal Polyps 		0.310 AlteredExpression phenotype BEFREE While APC/beta-CATENIN-dependent expression of CYCLIN D1 was observed in vivo and in vitro, expression of PPAR beta/delta was not different in colon or intestinal polyps from wild-type or Apc(min) heterozygous mice or in human colon cancer cell lines with mutations in APC and/or beta-CATENIN. 19415698 2009
CUI: C0021846
Disease: Intestinal Polyps
Intestinal Polyps 		0.310 Biomarker phenotype CTD_human Suppression of tumorigenesis in the Apc(min) mouse: down-regulation of beta-catenin signaling by a combination of tea plus sulindac. 12584176 2003