CCND1, cyclin D1, 595

N. diseases: 859; N. variants: 12
Disease: Keloid ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022548
Disease: Keloid
Keloid 		0.010 PosttranslationalModification disease BEFREE Functionally, targeting β-catenin with lipofection-delivered small interfering RNA oligonucleotide inhibited the proliferation and cell cycle arrest in G0/G1 phase and increased apoptosis of fibroblast cells, accompanied by downregulation of Wnt2 and cyclin D1 as well as the phosphorylation level of glycogen synthase kinase 3 beta in the keloid fibrosis. 28656880 2017