CCND1, cyclin D1, 595

N. diseases: 859; N. variants: 12
Disease: maladjustment ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0281902
Disease: maladjustment
maladjustment 		0.010 AlteredExpression phenotype BEFREE In this paper, results indicated that a c-Jun/Jun B heterodimer induced by LMP1 upregulated cyclin D1 promoters activity and expression, on the contrary, downregulated p16, and maladjustment of cyclin D1 and p16 expression accelerated progression of cell cycle. 15936839 2005