|
Gestational Diabetes
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
In this sense, 1st-2nd trimester-released biomarkers found in maternal plasma including adipose tissue-derived factors such as adiponectin, visfatin, omentin-1, fatty acid-binding protein-4 and retinol binding-protein-4 have shown correlations with GDM development.
|
31666083 |
2019 |
|
Gestational Diabetes
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
Then, ELISA assay indicated that the levels of serum RBP4, Hcy, GA and FFA were lower in PEP groups than GDM groups in a dose-dependent manner.
|
31632524 |
2019 |
|
Gestational Diabetes
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Levels of FINS and RBP4 in postpartum GDM group were higher than those in normal control group (P<0.05).
|
31700915 |
2019 |
|
Gestational Diabetes
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
There is evidence of a positive association of early pregnancy elevated RBP4 concentration with increased GDM risk, particularly among women with advanced age and obesity.
|
30428456 |
2019 |
|
Gestational Diabetes
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
Serum adiponectin was lower in women with GDM and GIGT at both 1-year and 3-years (both P ≤ 0.002), whereas chemerin, RBP-4, CRP and PAI-1 showed no differences across the 4 groups.
|
30301460 |
2018 |
|
Gestational Diabetes
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
The aim of this study was to evaluate the RBP4 and retinol level in rat model of gestational diabetes mellitus and the relationship between retinol-free RBP4 (apo-RBP4), retinol-bound RBP4 (holo-RBP4) and insulin resistance.
|
28528355 |
2017 |
|
Gestational Diabetes
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Our study supports a potentially promising role of sitagliptin in improving insulin resistance by decreasing RBP-4 in GDM-affected women.
|
28213841 |
2017 |
|
Gestational Diabetes
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
The meta-analysis on the association between rs3758539 polymorphism and GDM risk shows that RBP4 rs3758539 polymorphism is not associated with the development of GDM.
|
26975349 |
2016 |
|
Gestational Diabetes
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
Noncoding SNPs of the RBP4 gene are not associated with GDM, but two SNPs showed associations with insulin resistance and insulin levels in women with prior GDM.
|
24665145 |
2014 |
|
Gestational Diabetes
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
RBP4 mRNA expression in adipose tissue of GDM patients was significantly increased in comparison to control subjects (1.438 ± 0.187 vs 1.034 ± 0.062, p=0.025).
|
22444425 |
2012 |
|
Gestational Diabetes
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
In conclusion, our results suggest that the elevated expression of RBP4 in SAT may contribute to the increase in circulating RBP4 in GDM subjects.
|
21609194 |
2011 |
|
Gestational Diabetes
|
0.100 |
Biomarker
|
phenotype |
LHGDN |
High plasma retinol binding protein-4 and low plasma adiponectin concentrations are associated with severity of glucose intolerance in women with previous gestational diabetes mellitus.
|
18492757 |
2008 |
|
Gestational Diabetes
|
0.100 |
Biomarker
|
phenotype |
LHGDN |
Women with gestational diabetes had lower RBP4 EIA and western blot levels than controls (median 6.8 [interquartile range, 3.9-14.3] vs 11.3 [7.8-19.9] microg/ml, p < 0.001 and 25.1 [21.7-29.6] vs 26.6 [23.5-32.2] microg/ml, p = 0.026).
|
18437353 |
2008 |