BCL2, BCL2 apoptosis regulator, 596

N. diseases: 1456; N. variants: 27
Disease: Asthma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004096
Disease: Asthma
Asthma 		0.350 Biomarker disease BEFREE The aim of this study was to elucidate the effect of microRNA-23a (miR-23a) on BCL2, and CXCL12 in asthma. 31020662 2019
CUI: C0004096
Disease: Asthma
Asthma 		0.350 AlteredExpression disease BEFREE Collectively, these results showed that Bcl-2-caspase-9 apoptosis pathway was clearly activated in the testis of asthmatic mice with the increased expression of apoptosis-related genes and proteins. 26938720 2016
CUI: C0004096
Disease: Asthma
Asthma 		0.350 Biomarker disease CTD_human In asthmatic patients, elevated levels of interleukin-4 and up-regulated Bcl-2 expression were detected. 18357729 2008
CUI: C0004096
Disease: Asthma
Asthma 		0.350 AlteredExpression disease BEFREE Cyclosporin A, apoptosis of BAL T-cells and expression of Bcl-2 in asthmatics. 12952249 2003
CUI: C0004096
Disease: Asthma
Asthma 		0.350 Biomarker disease BEFREE In contrast, the Bcl-2 family of genes showed a net pro-apoptotic profile in AN and AA. 11207646 2001
CUI: C0004096
Disease: Asthma
Asthma 		0.350 AlteredExpression disease BEFREE Compared with control subjects or untreated patients, steroid-treated asthmatics exhibited increased expression of Bcl-2, Fas, FasL, and of proliferating cell nuclear antigen (PCNA) in their bronchial epithelium, without changes in the number of apoptotic cells. 9806739 1998