BCL2, BCL2 apoptosis regulator, 596

N. diseases: 1456; N. variants: 27
Disease: Presenile dementia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011265
Disease: Presenile dementia
Presenile dementia 		0.330 AlteredExpression disease BEFREE We stratified 75 brain tissues from Alzheimer's disease into hyperphosphorylated tau positive or negative and did co-expression analyses and qRTPCR for importin-β and exportin-5 plus several bcl2 family members and compared the data to controls, Down's dementia and Parkinson's disease. 29414391 2018
CUI: C0011265
Disease: Presenile dementia
Presenile dementia 		0.330 GeneticVariation disease BEFREE Effect of Bcl-2 rs956572 SNP on regional gray matter volumes and cognitive function in elderly males without dementia. 22198673 2013
CUI: C0011265
Disease: Presenile dementia
Presenile dementia 		0.330 Biomarker disease CTD_human Loss of phospholipid asymmetry and elevated brain apoptotic protein levels in subjects with amnestic mild cognitive impairment and Alzheimer disease. 18077176 2008
CUI: C0011265
Disease: Presenile dementia
Presenile dementia 		0.330 AlteredExpression disease BEFREE The expression of anti-apoptotic Bcl2 correlated with observed cell death in T-helper and B cells irrespective of dementia. 17124644 2006