BCL2, BCL2 apoptosis regulator, 596

N. diseases: 1456; N. variants: 27
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024302
Disease: Reticulosarcoma
Reticulosarcoma
0.350 Biomarker disease CTD_human Copper-64-labeled anti-bcl-2 PNA-peptide conjugates selectively localize to bcl-2-positive tumors in mouse models of B-cell lymphoma. 26239085 2015
CUI: C0024302
Disease: Reticulosarcoma
Reticulosarcoma
0.350 GeneticVariation disease BEFREE In this study, by using polymerase chain reaction and fluorescence in situ hybridization techniques, we have showed that there is neither t(14;18)/IGH-BCL2 nor IGH gene rearrangement in 4 de novo IDCS without a concurrent or known history of a B-cell lymphoma, including follicular lymphoma, indicating that BCL2 chromosomal translocation is not a general feature of de novo IDCS. 20736747 2010
CUI: C0024302
Disease: Reticulosarcoma
Reticulosarcoma
0.350 AlteredExpression disease BEFREE Incidence of Epstein-Barr virus bcl-2 expression and chromosomal translocation t(14;18) in large cell lymphoma associated with paragranuloma (lymphocyte-predominant Hodgkin's disease). 8150454 1994
CUI: C0024302
Disease: Reticulosarcoma
Reticulosarcoma
0.350 GeneticVariation disease BEFREE The difference of bcl-2 rearrangement frequency between follicular, mixed and large cell lymphoma was also statistically significant (P = 0.012). 8449825 1993
CUI: C0024302
Disease: Reticulosarcoma
Reticulosarcoma
0.350 GeneticVariation disease BEFREE There was only one large-cell lymphoma with a bcl-2 rearrangement. 2200538 1990
CUI: C0024302
Disease: Reticulosarcoma
Reticulosarcoma
0.350 GeneticVariation disease BEFREE bcl-2 and other genomic alterations in the prognosis of large-cell lymphoma. 2648153 1989
CUI: C0024302
Disease: Reticulosarcoma
Reticulosarcoma
0.350 Biomarker disease CTD_human Expression in non-Hodgkin's lymphoma of the bcl-2 protein associated with the t(14;18) chromosomal translocation. 3287162 1988