BCL2, BCL2 apoptosis regulator, 596

N. diseases: 1294; N. variants: 19
Disease: Schizophrenia ×
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.320 AlteredExpression disease BEFREE ADNP haploinsufficiency in mice, which results in age-related neuronal death, cognitive and social dysfunction, exhibited reduced hippocampal beclin1 and increased Bcl2 expression (mimicking schizophrenia and normal human aging). 24365867 2015
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.320 AlteredExpression disease BEFREE There have been lower Bcl-2 levels and increased Bax/Bcl-2 ratio in the temporal cortex of patients with schizophrenia compared with those in controls. 19632297 2009