REL, REL proto-oncogene, NF-kB subunit, 5966

N. diseases: 90; N. variants: 5
Disease: Autoimmune Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.120 AlteredExpression group BEFREE However, despite the highly reduced Treg compartment, double-deficient mice did not develop autoimmunity even when aged to more than 1 y, suggesting that c-REL and IκB<sub>NS</sub> are required for T cell effector function as well. 28652399 2017
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.120 GeneticVariation group BEFREE Genome-wide association studies (GWAS) and candidate gene studies have identified the REL and PRKCQ genes as risk loci for various autoimmune diseases. 26784953 2016
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.120 GeneticVariation group GWASDB Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. 21383967 2011